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Hypoxia regulates the degradation of non-nuclear organelles during lens differentiation through activation of HIF1a.

Formation of the eye lens depends on the continuous differentiation of lens epithelial cells into lens fiber cells. To attain their mature structure and transparent function, nascent lens fiber cells must complete a precise cellular remodeling program hallmarked by the complete elimination of organe...

詳細記述

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書誌詳細
出版年:Exp Eye Res
主要な著者: Brennan, Lisa, Disatham, Joshua, Kantorow, Marc
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508769/
https://ncbi.nlm.nih.gov/pubmed/32628953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.108129
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