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Computational biotechnology guides elucidation of the biosynthesis of the plant anticancer drug camptothecin

Camptothecin is a clinically important monoterpene indole alkaloid (MIAs) used for treating various cancers. Currently, the production of this biopharmaceutical hinges on its extraction from camptothecin-producing plants, leading to high market prices and supply bottlenecks. While synthetic biology...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Stander, Emily Amor, Dugé de Bernonville, Thomas, Papon, Nicolas, Courdavault, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254074/
https://ncbi.nlm.nih.gov/pubmed/34257844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.06.028
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