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Computational biotechnology guides elucidation of the biosynthesis of the plant anticancer drug camptothecin

Camptothecin is a clinically important monoterpene indole alkaloid (MIAs) used for treating various cancers. Currently, the production of this biopharmaceutical hinges on its extraction from camptothecin-producing plants, leading to high market prices and supply bottlenecks. While synthetic biology...

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Podrobná bibliografie
Vydáno v:Comput Struct Biotechnol J
Hlavní autoři: Stander, Emily Amor, Dugé de Bernonville, Thomas, Papon, Nicolas, Courdavault, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: Research Network of Computational and Structural Biotechnology 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254074/
https://ncbi.nlm.nih.gov/pubmed/34257844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.06.028
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