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Coupling size exclusion chromatography to ultracentrifugation improves detection of exosomal proteins from human plasma by LC-MS

OBJECTIVES: Exosomes are small lipid bilayer vesicles that are defined by their endocytic origin and size range of 30–140 nm. They are constantly produced by different cell types, by both healthy and abnormal cells, and can be isolated from almost all body fluids. Little information exists in isolat...

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Bibliografische gegevens
Gepubliceerd in:Pract Lab Med
Hoofdauteurs: Alameldin, Sara, Costina, Victor, Abdel-Baset, Hesham A., Nitschke, Katja, Nuhn, Phillip, Neumaier, Michael, Hedtke, Maren
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254000/
https://ncbi.nlm.nih.gov/pubmed/34258353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plabm.2021.e00241
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