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Coupling size exclusion chromatography to ultracentrifugation improves detection of exosomal proteins from human plasma by LC-MS

OBJECTIVES: Exosomes are small lipid bilayer vesicles that are defined by their endocytic origin and size range of 30–140 nm. They are constantly produced by different cell types, by both healthy and abnormal cells, and can be isolated from almost all body fluids. Little information exists in isolat...

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Bibliographische Detailangaben
Veröffentlicht in:Pract Lab Med
Hauptverfasser: Alameldin, Sara, Costina, Victor, Abdel-Baset, Hesham A., Nitschke, Katja, Nuhn, Phillip, Neumaier, Michael, Hedtke, Maren
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8254000/
https://ncbi.nlm.nih.gov/pubmed/34258353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plabm.2021.e00241
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