Differential ATAC-seq and ChIP-seq peak detection using ROTS

Changes in cellular chromatin states fine-tune transcriptional output and ultimately lead to phenotypic changes. Here we propose a novel application of our reproducibility-optimized test statistics (ROTS) to detect differential chromatin states (ATAC-seq) or differential chromatin modification state...

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Udgivet i:NAR Genom Bioinform
Main Authors: Faux, Thomas, Rytkönen, Kalle T, Mahmoudian, Mehrad, Paulin, Niklas, Junttila, Sini, Laiho, Asta, Elo, Laura L
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Methods Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253552/
https://ncbi.nlm.nih.gov/pubmed/34235431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqab059
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