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Combined Inhibition of Akt and mTOR Is Effective Against Non-Hodgkin Lymphomas

Non-Hodgkin lymphoma (NHL) are a diverse group of hematological malignancies comprised of over 60 subtypes. These subtypes range from indolent to aggressive. The PI3K/Akt/mTOR pathway has been shown to contribute to cell survival and proliferation and is constitutively active in most NHL. MK-7075 (m...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Rivera-Soto, Ricardo, Yu, Yi, Dittmer, Dirk P., Damania, Blossom
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253055/
https://ncbi.nlm.nih.gov/pubmed/34221985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.670275
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