Apical CLC‐2 in retinal pigment epithelium is crucial for survival of the outer retina

Knockout of the chloride channel protein 2 (CLC‐2; CLCN2) results in fast progressing blindness in mice. Retinal Pigment Epithelium (RPE) and photoreceptors undergo, in parallel, rapid, and profound morphological changes and degeneration. Immunohistochemistry and electron microscopy of the outer ret...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:FASEB J
Päätekijät: Hanke‐Gogokhia, Christin, Lehmann, Guillermo L., Benedicto, Ignacio, de la Fuente‐Ortega, Erwin, Arshavsky, Vadim Y., Schreiner, Ryan, Rodriguez‐Boulan, Enrique
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2021
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252757/
https://ncbi.nlm.nih.gov/pubmed/34085737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202100349R
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