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Redox‐Neutral Selenium‐Catalysed Isomerisation of para‐Hydroxamic Acids into para‐Aminophenols

A selenium‐catalysed para‐hydroxylation of N‐aryl‐hydroxamic acids is reported. Mechanistically, the reaction comprises an N−O bond cleavage and consecutive selenium‐induced [2,3]‐rearrangement to deliver para‐hydroxyaniline derivatives. The mechanism is studied through both (18)O‐crossover experime...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Chuang, Hsiang‐Yu, Schupp, Manuel, Meyrelles, Ricardo, Maryasin, Boris, Maulide, Nuno
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252732/
https://ncbi.nlm.nih.gov/pubmed/33760338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202100801
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