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Direct Catalytic N‐Alkylation of α‐Amino Acid Esters and Amides Using Alcohols with High Retention of Stereochemistry

The direct functionalization of naturally abundant chiral scaffolds such as α‐amino acid esters or amides with widely abundant alcohols, without any racemization, is a demanding transformation that is of central importance for the synthesis of bio‐active compounds. Herein a robust and general method...

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Detalhes bibliográficos
Publicado no:ChemSusChem
Main Authors: Yan, Tao, Feringa, Ben L., Barta, Katalin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252633/
https://ncbi.nlm.nih.gov/pubmed/33961350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cssc.202100373
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