Ruthenium and Iron‐Catalysed Decarboxylative N‐alkylation of Cyclic α‐Amino Acids with Alcohols: Sustainable Routes to Pyrrolidine and Piperidine Derivatives

A modular and waste‐free strategy for constructing N‐substituted cyclic amines via decarboxylative N‐alkylation of α‐amino acids employing ruthenium‐ and iron‐based catalysts is presented. The reported method allows the synthesis of a wide range of five‐ and six‐membered N‐alkylated heterocycles in...

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Bibliographic Details
Published in:ChemSusChem
Main Authors: Afanasenko, Anastasiia, Hannah, Rachael, Yan, Tao, Elangovan, Saravanakumar, Barta, Katalin
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772061/
https://ncbi.nlm.nih.gov/pubmed/31328892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cssc.201901499
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