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Rerouting and Improving Dauc‐8‐en‐11‐ol Synthase from Streptomyces venezuelae to a High Yielding Biocatalyst

The dauc‐8‐en‐11‐ol synthase from Streptomyces venezuelae was investigated for its catalytic activity towards alternative terpene precursors, specifically designed to enable new cyclisation pathways. Exchange of aromatic amino acid residues at the enzyme surface by site‐directed mutagenesis led to a...

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Bibliografiset tiedot
Julkaisussa:Chemistry
Päätekijät: Lauterbach, Lukas, Hou, Anwei, Dickschat, Jeroen S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252471/
https://ncbi.nlm.nih.gov/pubmed/33769623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202100962
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