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The Biosynthetic Gene Cluster for Sestermobaraenes—Discovery of a Geranylfarnesyl Diphosphate Synthase and a Multiproduct Sesterterpene Synthase from Streptomyces mobaraensis

A biosynthetic gene cluster from Streptomyces mobaraensis encoding the first cases of a bacterial geranylfarnesyl diphosphate synthase and a type I sesterterpene synthase was identified. The structures of seven sesterterpenes produced by these enzymes were elucidated, including their absolute config...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Hou, Anwei, Dickschat, Jeroen S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693059/
https://ncbi.nlm.nih.gov/pubmed/32749032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202010084
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