The energy sensor AMPK orchestrates metabolic and translational adaptation in expanding T helper cells

The importance of cellular metabolic adaptation in inducing robust T cell responses is well established. However, the mechanism by which T cells link information regarding nutrient supply to clonal expansion and effector function is still enigmatic. Herein, we report that the metabolic sensor adenos...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Mayer, Katharina A., Smole, Ursula, Zhu, Ci, Derdak, Sophia, Minervina, Anastasia A., Salnikova, Maria, Witzeneder, Nadine, Christamentl, Anna, Boucheron, Nicole, Waidhofer‐Söllner, Petra, Trauner, Michael, Hoermann, Gregor, Schmetterer, Klaus G., Mamedov, Ilgar Z., Bilban, Martin, Ellmeier, Wilfried, Pickl, Winfried F., Gualdoni, Guido A., Zlabinger, Gerhard J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252394/
https://ncbi.nlm.nih.gov/pubmed/33715236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001763RR
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