Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome

INTRODUCTION: Adults with Down syndrome are genetically predisposed to develop Alzheimer’s disease and accumulate beta-amyloid plaques (Aβ) early in life. While Aβ has been heavily studied in Down syndrome, its relationship with neurofibrillary tau is less understood. The aim of this study was to ev...

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Bibliografiska uppgifter
I publikationen:Neuroimage Clin
Huvudupphovsmän: Zammit, Matthew D., Tudorascu, Dana L., Laymon, Charles M., Hartley, Sigan L., Ellison, Paul A., Zaman, Shahid H., Ances, Beau M., Johnson, Sterling C., Stone, Charles K., Sabbagh, Marwan N., Mathis, Chester A., Klunk, William E., Cohen, Ann D., Handen, Benjamin L., Christian, Bradley T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2021
Ämnen:
Regular Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8252122/
https://ncbi.nlm.nih.gov/pubmed/34182407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2021.102740
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