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Light‐Activation of DNA‐Methyltransferases

5‐Methylcytosine (5mC), the central epigenetic mark of mammalian DNA, plays fundamental roles in chromatin regulation. 5mC is written onto genomes by DNA methyltransferases (DNMT), and perturbation of this process is an early event in carcinogenesis. However, studying 5mC functions is limited by the...

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Dettagli Bibliografici
Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Wolffgramm, Jan, Buchmuller, Benjamin, Palei, Shubhendu, Muñoz‐López, Álvaro, Kanne, Julian, Janning, Petra, Schweiger, Michal R., Summerer, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8251764/
https://ncbi.nlm.nih.gov/pubmed/33826797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202103945
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