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Drug synergy of combinatory treatment with remdesivir and the repurposed drugs fluoxetine and itraconazole effectively impairs SARS‐CoV‐2 infection in vitro

BACKGROUND AND PURPOSE: The SARS‐COV‐2 pandemic and the global spread of coronavirus disease 2019 (COVID‐19) urgently call for efficient and safe antiviral treatment strategies. A straightforward approach to speed up drug development at lower costs is drug repurposing. Here, we investigated the ther...

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Опубликовано в: :Br J Pharmacol
Главные авторы: Schloer, Sebastian, Brunotte, Linda, Mecate‐Zambrano, Angeles, Zheng, Shuyu, Tang, Jing, Ludwig, Stephan, Rescher, Ursula
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8251190/
https://ncbi.nlm.nih.gov/pubmed/33825201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15418
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