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Neutralising antibody escape of SARS‐CoV‐2 spike protein: Risk assessment for antibody‐based Covid‐19 therapeutics and vaccines

The Spike protein is the target of both antibody‐based therapeutics (convalescent plasma, polyclonal serum, monoclonal antibodies) and vaccines. Mutations in Spike could affect efficacy of those treatments. Hence, monitoring of mutations is necessary to forecast and readapt the inventory of therapeu...

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Detalhes bibliográficos
Publicado no:Rev Med Virol
Main Authors: Focosi, Daniele, Maggi, Fabrizio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8250244/
https://ncbi.nlm.nih.gov/pubmed/33724631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rmv.2231
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