Chronic Immune Activation and CD4(+) T Cell Lymphopenia in Healthy African Individuals: Perspectives for SARS-CoV-2 Vaccine Efficacy

Chronic immune activation has been considered as the driving force for CD4(+) T cell depletion in people infected with HIV-1. Interestingly, the normal immune profile of adult HIV-negative individuals living in Africa also exhibit chronic immune activation, reminiscent of that observed in HIV-1 infe...

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Vydáno v:Front Immunol
Hlavní autoři: Wolday, Dawit, Ndungu, Francis M., Gómez-Pérez, Gloria P., de Wit, Tobias F. Rinke
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249933/
https://ncbi.nlm.nih.gov/pubmed/34220854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.693269
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