Genome stabilization by RAD51‐stimulatory compound 1 enhances efficiency of somatic cell nuclear transfer‐mediated reprogramming and full‐term development of cloned mouse embryos

OBJECTIVES: The genetic instability and DNA damage arise during transcription factor‐mediated reprogramming of somatic cells, and its efficiency may be reduced due to abnormal chromatin remodelling. The efficiency in somatic cell nuclear transfer (SCNT)‐mediated reprogramming is also very low, and i...

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Bibliografiske detaljer
Udgivet i:Cell Prolif
Main Authors: Lee, Ah Reum, Park, Ji‐Hoon, Shim, Sung Han, Hong, Kwonho, La, Hyeonwoo, Park, Kyung‐Soon, Lee, Dong Ryul
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249786/
https://ncbi.nlm.nih.gov/pubmed/34021643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.13059
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