Genome stabilization by RAD51‐stimulatory compound 1 enhances efficiency of somatic cell nuclear transfer‐mediated reprogramming and full‐term development of cloned mouse embryos

OBJECTIVES: The genetic instability and DNA damage arise during transcription factor‐mediated reprogramming of somatic cells, and its efficiency may be reduced due to abnormal chromatin remodelling. The efficiency in somatic cell nuclear transfer (SCNT)‐mediated reprogramming is also very low, and i...

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Dades bibliogràfiques
Publicat a:Cell Prolif
Autors principals: Lee, Ah Reum, Park, Ji‐Hoon, Shim, Sung Han, Hong, Kwonho, La, Hyeonwoo, Park, Kyung‐Soon, Lee, Dong Ryul
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249786/
https://ncbi.nlm.nih.gov/pubmed/34021643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.13059
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