COVID-19 vaccine mRNA-1273 elicits a protective immune profile in mice that is not associated with vaccine-enhanced disease upon SARS-CoV-2 challenge

Vaccine-associated enhanced respiratory disease (VAERD) was previously observed in some preclinical models of severe acute respiratory syndrome (SARS) and MERS coronavirus vaccines. We used the SARS coronavirus 2 (SARS-CoV-2) mouse-adapted, passage 10, lethal challenge virus (MA10) mouse model of ac...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Immunity
Autors principals: DiPiazza, Anthony T., Leist, Sarah R., Abiona, Olubukola M., Moliva, Juan I., Werner, Anne, Minai, Mahnaz, Nagata, Bianca M., Bock, Kevin W., Phung, Emily, Schäfer, Alexandra, Dinnon, Kenneth H., Chang, Lauren A., Loomis, Rebecca J., Boyoglu-Barnum, Seyhan, Alvarado, Gabriela S., Sullivan, Nancy J., Edwards, Darin K., Morabito, Kaitlyn M., Mascola, John R., Carfi, Andrea, Corbett, Kizzmekia S., Moore, Ian N., Baric, Ralph S., Graham, Barney S., Ruckwardt, Tracy J.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249710/
https://ncbi.nlm.nih.gov/pubmed/34270939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.06.018
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars