The Combination Treatment of Curcumin and Probucol Protects Chondrocytes from TNF-α Induced Inflammation by Enhancing Autophagy and Reducing Apoptosis via the PI3K-Akt-mTOR Pathway

Osteoarthritis (OA) is a chronic joint disease characterized by cholesterol accumulation in chondrocytes, cartilage degeneration, as well as extracellular matrix (ECM) destruction, and joint dysfunction. Curcumin, a chemical that can reduce cholesterol levels in OA patients, also can inhibit the pro...

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Foilsithe in:Oxid Med Cell Longev
Main Authors: Han, Guangtao, Zhang, Yubiao, Li, Haohuan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Hindawi 2021
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8249126/
https://ncbi.nlm.nih.gov/pubmed/34257809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5558066
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