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Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations
Most cancer chemotherapeutic agents are ineffective in a subset of patients; thus, it is important to consider the role of genetic variation in drug response. Lymphoblastoid cell lines (LCLs) in 1000 Genomes Project populations of diverse ancestries are a useful model for determining how genetic fac...
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| Publié dans: | Hum Mol Genet |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8248963/ https://ncbi.nlm.nih.gov/pubmed/33575800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddab029 |
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