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Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations

Most cancer chemotherapeutic agents are ineffective in a subset of patients; thus, it is important to consider the role of genetic variation in drug response. Lymphoblastoid cell lines (LCLs) in 1000 Genomes Project populations of diverse ancestries are a useful model for determining how genetic fac...

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Foilsithe in:Hum Mol Genet
Main Authors: Mulford, Ashley J, Wing, Claudia, Dolan, M Eileen, Wheeler, Heather E
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248963/
https://ncbi.nlm.nih.gov/pubmed/33575800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddab029
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