Enhanced IL-1β Release Following NLRP3 and AIM2 Inflammasome Stimulation Is Linked to mtROS in Airway Macrophages in Pulmonary Fibrosis

Fibrotic Interstitial lung diseases (ILDs) are complex disorders of variable clinical behaviour. The majority of them cause significant morbidity, whilst Idiopathic Pulmonary Fibrosis (IPF) is recognised as the most relentless. NLRP3, AIM2, and NLRC4 inflammasomes are multiprotein complexes driving...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Trachalaki, Athina, Tsitoura, Eliza, Mastrodimou, Semeli, Invernizzi, Rachele, Vasarmidi, Eirini, Bibaki, Eleni, Tzanakis, Nikolaos, Molyneaux, Philip L., Maher, Toby M., Antoniou, Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248801/
https://ncbi.nlm.nih.gov/pubmed/34220810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.661811
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