Enhanced IL-1β Release Following NLRP3 and AIM2 Inflammasome Stimulation Is Linked to mtROS in Airway Macrophages in Pulmonary Fibrosis

Fibrotic Interstitial lung diseases (ILDs) are complex disorders of variable clinical behaviour. The majority of them cause significant morbidity, whilst Idiopathic Pulmonary Fibrosis (IPF) is recognised as the most relentless. NLRP3, AIM2, and NLRC4 inflammasomes are multiprotein complexes driving...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Trachalaki, Athina, Tsitoura, Eliza, Mastrodimou, Semeli, Invernizzi, Rachele, Vasarmidi, Eirini, Bibaki, Eleni, Tzanakis, Nikolaos, Molyneaux, Philip L., Maher, Toby M., Antoniou, Katerina
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248801/
https://ncbi.nlm.nih.gov/pubmed/34220810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.661811
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