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Epigenomic reprogramming as a driver of malignant glioma

Malignant gliomas are central nervous system tumors and remain amongst the most treatment-resistant cancers. Exome sequencing has revealed significant heterogeneity and important insights into the molecular pathogenesis of gliomas. Mutations in chromatin modifiers – proteins that shape the epigenomi...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Phillips, Richard E., Soshnev, Alexey A., Allis, C. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248764/
https://ncbi.nlm.nih.gov/pubmed/32916125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.08.008
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