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lra: A long read aligner for sequences and contigs

It is computationally challenging to detect variation by aligning single-molecule sequencing (SMS) reads, or contigs from SMS assemblies. One approach to efficiently align SMS reads is sparse dynamic programming (SDP), where optimal chains of exact matches are found between the sequence and the geno...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Ren, Jingwen, Chaisson, Mark J. P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248648/
https://ncbi.nlm.nih.gov/pubmed/34153026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1009078
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