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Assembly of chromosome-scale contigs by efficiently resolving repetitive sequences with long reads

The abundant repetitive sequences in complex eukaryotic genomes cause fragmented assemblies, which lose value as reference genomes, often due to incomplete gene sequences and unanchored or mispositioned contigs on chromosomes. Here we report a genome assembly method HERA, which resolves repeats effi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Du, Huilong, Liang, Chengzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877557/
https://ncbi.nlm.nih.gov/pubmed/31767853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13355-3
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