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Assembly of chromosome-scale contigs by efficiently resolving repetitive sequences with long reads

The abundant repetitive sequences in complex eukaryotic genomes cause fragmented assemblies, which lose value as reference genomes, often due to incomplete gene sequences and unanchored or mispositioned contigs on chromosomes. Here we report a genome assembly method HERA, which resolves repeats effi...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Du, Huilong, Liang, Chengzhi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877557/
https://ncbi.nlm.nih.gov/pubmed/31767853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13355-3
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