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Delineation of the functional properties exhibited by the Zinc-Activated Channel (ZAC) and its high-frequency Thr(128)Ala variant (rs2257020) in Xenopus oocytes
The signalling characteristics of the Zinc-Activated Channel (ZAC), a member of the Cys-loop receptor (CLR) superfamily, are presently poorly elucidated. The ZACN polymorphism c.454G>A encoding for the Thr(128)Ala variation in ZAC is found in extremely high allele frequencies across ethnicities....
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| Veröffentlicht in: | Pharmacol Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8248299/ https://ncbi.nlm.nih.gov/pubmed/33962015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2021.105653 |
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