Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease

Intron retention (IR) has been implicated in the pathogenesis of complex diseases such as cancers; its association with Alzheimer's disease (AD) remains unexplored. We performed genome‐wide analysis of IR through integrating genetic, transcriptomic, and proteomic data of AD subjects and mouse m...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Li, Hong‐Dong, Funk, Cory C., McFarland, Karen, Dammer, Eric B., Allen, Mariet, Carrasquillo, Minerva M., Levites, Yona, Chakrabarty, Paramita, Burgess, Jeremy D., Wang, Xue, Dickson, Dennis, Seyfried, Nicholas T., Duong, Duc M., Lah, James J., Younkin, Steven G., Levey, Allan I., Omenn, Gilbert S., Ertekin‐Taner, Nilüfer, Golde, Todd E., Price, Nathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248162/
https://ncbi.nlm.nih.gov/pubmed/33480174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12254
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