Acetazolamide Improves Right Ventricular Function and Metabolic Gene Dysregulation in Experimental Pulmonary Arterial Hypertension

Background: Right ventricular (RV) performance is a key determinant of mortality in pulmonary arterial hypertension (PAH). RV failure is characterized by metabolic dysregulation with unbalanced anaerobic glycolysis, oxidative phosphorylation, and fatty acid oxidation (FAO). We previously found that...

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Bibliografiske detaljer
Udgivet i:Front Cardiovasc Med
Main Authors: Spyropoulos, Fotios, Michael, Zoe, Finander, Benjamin, Vitali, Sally, Kosmas, Kosmas, Zymaris, Panagiotis, Kalish, Brian T., Kourembanas, Stella, Christou, Helen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Cardiovascular Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247952/
https://ncbi.nlm.nih.gov/pubmed/34222363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.662870
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