Acetazolamide Improves Right Ventricular Function and Metabolic Gene Dysregulation in Experimental Pulmonary Arterial Hypertension

Background: Right ventricular (RV) performance is a key determinant of mortality in pulmonary arterial hypertension (PAH). RV failure is characterized by metabolic dysregulation with unbalanced anaerobic glycolysis, oxidative phosphorylation, and fatty acid oxidation (FAO). We previously found that...

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Detalhes bibliográficos
Publicado no:Front Cardiovasc Med
Main Authors: Spyropoulos, Fotios, Michael, Zoe, Finander, Benjamin, Vitali, Sally, Kosmas, Kosmas, Zymaris, Panagiotis, Kalish, Brian T., Kourembanas, Stella, Christou, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cardiovascular Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247952/
https://ncbi.nlm.nih.gov/pubmed/34222363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.662870
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