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Oral administration of amphotericin B nanoparticles: antifungal activity, bioavailability and toxicity in rats

Amphotericin B (AMB) is used most commonly in severe systemic life-threatening fungal infections. There is currently an unmet need for an efficacious (AMB) formulation amenable to oral administration with better bioavailability and lower nephrotoxicity. Novel PEGylated polylactic-polyglycolic acid c...

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Dades bibliogràfiques
Publicat a:Drug Deliv
Autors principals: Radwan, Mahasen A., AlQuadeib, Bushra T., Šiller, Lidija, Wright, Matthew C., Horrocks, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247729/
https://ncbi.nlm.nih.gov/pubmed/28155565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2016.1228715
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