Identification of gene targets of developmental neurotoxicity focusing on DNA hypermethylation involved in irreversible disruption of hippocampal neurogenesis in rats

We have previously found that maternal exposure to 6‐propyl‐2‐thiouracil (PTU), valproic acid (VPA), or glycidol (GLY) has a sustained or late effect on hippocampal neurogenesis at the adult stage in rat offspring. Herein, we searched for genes with hypermethylated promoter region and downregulated...

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Detaylı Bibliyografya
Yayımlandı:J Appl Toxicol
Asıl Yazarlar: Kikuchi, Satomi, Takahashi, Yasunori, Ojiro, Ryota, Takashima, Kazumi, Okano, Hiromu, Tang, Qian, Woo, Gye‐Hyeong, Yoshida, Toshinori, Shibutani, Makoto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247304/
https://ncbi.nlm.nih.gov/pubmed/33150595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.4089
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