Ne-22 Ion-Beam Radiation Damage to DNA: From Initial Free Radical Formation to Resulting DNA-Base Damage

[Image: see text] We report on the physicochemical processes and the products of DNA damage involved in Ne-22 ion-beam radiation of hydrated (12 ± 3 H(2)O/nucleotide) salmon testes DNA at 77 K. Free radicals trapped at 77 K were identified using electron spin resonance (ESR) spectroscopy. The measur...

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Veröffentlicht in:ACS Omega
Hauptverfasser: Kant, Melis, Jaruga, Pawel, Coskun, Erdem, Ward, Samuel, Stark, Alexander D., Baumann, Thomas, Becker, David, Adhikary, Amitava, Sevilla, Michael D., Dizdaroglu, Miral
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2021
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246699/
https://ncbi.nlm.nih.gov/pubmed/34235332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c01954
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