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The blood–brain barrier and blood–tumour barrier in brain tumours and metastases
For a blood-borne cancer therapeutic agent to be effective, it must cross the blood vessel wall to reach cancer cells in adequate quantities, and it must overcome the resistance conferred by the local microenvironment around cancer cells. The brain microenvironment can thwart the effectiveness of dr...
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| Publicado no: | Nat Rev Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8246629/ https://ncbi.nlm.nih.gov/pubmed/31601988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41568-019-0205-x |
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