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Targeted therapy in SDH-deficient GIST
The medical management of advanced gastrointestinal stromal tumors (GIST) has improved with the development of tyrosine kinase inhibitors (TKIs) targeting KIT and PDGFRA mutations. However, approximately 5–10% of GIST lack KIT and PDGFRA mutations, and about a half are deficient in succinate dehydro...
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| Publicado no: | Ther Adv Med Oncol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8246492/ https://ncbi.nlm.nih.gov/pubmed/34262616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/17588359211023278 |
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