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Glycan–protein cross-linking mass spectrometry reveals sialic acid-mediated protein networks on cell surfaces

A cross-linking method is developed to elucidate glycan-mediated interactions between membrane proteins through sialic acids. The method provides information on previously unknown extensive glycomic interactions on cell membranes. The vast majority of membrane proteins are glycosylated with complica...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Xie, Yixuan, Chen, Siyu, Li, Qiongyu, Sheng, Ying, Alvarez, Michael Russelle, Reyes, Joeriggo, Xu, Gege, Solakyildirim, Kemal, Lebrilla, Carlito B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246274/
https://ncbi.nlm.nih.gov/pubmed/34257876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc00814e
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