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Dual roles of HSP70 chaperone HSPA1 in quality control of nascent and newly synthesized proteins

Exposure to heat stress triggers a well‐defined acute response marked by HSF1‐dependent transcriptional upregulation of heat shock proteins. Cells allowed to recover acquire thermotolerance, but this adaptation is poorly understood. By quantitative proteomics, we discovered selective upregulation of...

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Podrobná bibliografie
Vydáno v:EMBO J
Hlavní autoři: Tian, Guiyou, Hu, Cheng, Yun, Yun, Yang, Wensheng, Dubiel, Wolfgang, Cheng, Yabin, Wolf, Dieter A
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246255/
https://ncbi.nlm.nih.gov/pubmed/34010456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106183
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