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Dual roles of HSP70 chaperone HSPA1 in quality control of nascent and newly synthesized proteins

Exposure to heat stress triggers a well‐defined acute response marked by HSF1‐dependent transcriptional upregulation of heat shock proteins. Cells allowed to recover acquire thermotolerance, but this adaptation is poorly understood. By quantitative proteomics, we discovered selective upregulation of...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Tian, Guiyou, Hu, Cheng, Yun, Yun, Yang, Wensheng, Dubiel, Wolfgang, Cheng, Yabin, Wolf, Dieter A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246255/
https://ncbi.nlm.nih.gov/pubmed/34010456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106183
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