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NF-κB and NLRP3 gene expression changes during warm hepatic ischemia-reperfusion in rats with and without silibinin

AIM: This research examined silibinin's anti-inflammatory outcomes on the NOD-like receptor protein-3 (NLRP3) and NF-κB gene expression, which plays a notable role in inciting inflammatory pathways. BACKGROUND: Hepatic ischemia-reperfusion (I/R) is a common phenomenon in many clinical cases, in...

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Vydáno v:Gastroenterol Hepatol Bed Bench
Hlavní autoři: Zarpou, Setareh, Mosavi, Hadis, Bagheri, Abouzar, Malekzadeh Shafaroudi, Majid, Khonakdar-Tarsi, Abbas
Médium: Artigo
Jazyk:Inglês
Vydáno: Shaheed Beheshti University of Medical Sciences 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245836/
https://ncbi.nlm.nih.gov/pubmed/34221267
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