A Randomized, Double-Blind, Single-Dose Study Comparing the Biosimilarity of HOT-1010 With Bevacizumab (Avastin®) in Chinese Healthy Male Subjects

Objective: This study was conducted to compare the pharmacokinetics, safety and immunogenicity of HOT-1010 with bevacizumab (Avastin®) in Chinese healthy male subjects. Methods: A single-center, randomized, double-blind, single-dose, parallel trial was performed in 84 Chinese healthy male subjects w...

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Vydáno v:Front Pharmacol
Hlavní autoři: Huang, Kai, Que, Linling, Ding, Ying, Chu, Nannan, Qian, Zhenzhong, Shi, Yunfei, Qin, Wei, Li, Zhenni, Chen, Yuanxin, Gu, Xianghong, Wang, Jiakun, Zhang, Lin, Zhang, Jisheng, Zhu, Xiangyang, Yang, Yongmin, Tang, Yuan, He, Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245695/
https://ncbi.nlm.nih.gov/pubmed/34220519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.694375
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