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Age-dependent shift in the de novo proteome accompanies pathogenesis in an Alzheimer’s disease mouse model

Alzheimer’s disease (AD) is an age-related neurodegenerative disorder associated with memory loss, but the AD-associated neuropathological changes begin years before memory impairments. Investigation of the early molecular abnormalities in AD might offer innovative opportunities to target memory imp...

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Bibliografiske detaljer
Udgivet i:Commun Biol
Main Authors: Elder, Megan K., Erdjument-Bromage, Hediye, Oliveira, Mauricio M., Mamcarz, Maggie, Neubert, Thomas A., Klann, Eric
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245541/
https://ncbi.nlm.nih.gov/pubmed/34193971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02324-6
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