Auranofin prevents liver fibrosis by system Xc-mediated inhibition of NLRP3 inflammasome

Demand for a cure of liver fibrosis is rising with its increasing morbidity and mortality. Therefore, it is an urgent issue to investigate its therapeutic candidates. Liver fibrosis progresses following ‘multi-hit’ processes involving hepatic stellate cells, macrophages, and hepatocytes. The NOD-lik...

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Publicado no:Commun Biol
Main Authors: Kim, Hyun Young, Choi, Young Jae, Kim, Sang Kyum, Kim, Hyunsung, Jun, Dae Won, Yoon, Kyungrok, Kim, Nayoun, Hwang, Jungwook, Kim, Young-Mi, Lim, Sung Chul, Kang, Keon Wook
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245406/
https://ncbi.nlm.nih.gov/pubmed/34193972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02345-1
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