Auranofin Inhibits RANKL-Induced Osteoclastogenesis by Suppressing Inhibitors of κB Kinase and Inflammasome-Mediated Interleukin-1β Secretion

Osteoporosis is a degenerative metabolic disease caused by an imbalance between osteogenesis and osteoclastogenesis. Increased levels of proinflammatory cytokines combined with decreased estrogen levels, which are commonly seen in postmenopausal women, can lead to overactivation of osteoclasts. Ther...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Kim, Hyun Young, Kim, Kyeong Seok, Kim, Myung Ji, Kim, Hyung-Shik, Lee, Kwang-Youl, Kang, Keon Wook
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561666/
https://ncbi.nlm.nih.gov/pubmed/31275508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3503912
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