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Trolox Prevents Osteoclastogenesis by Suppressing RANKL Expression and Signaling

Excessive receptor activator of NF-κB ligand (RANKL) signaling causes enhanced osteoclast formation and bone resorption. Thus, down-regulation of RANKL expression or its downstream signals may be a therapeutic approach to the treatment of pathological bone loss. In this study, we investigated the ef...

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Detalhes bibliográficos
Main Authors: Lee, Jong-Ho, Kim, Ha-Neui, Yang, Daum, Jung, Kyoungsuk, Kim, Hyun-Man, Kim, Hong-Hee, Ha, Hyunil, Lee, Zang Hee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679474/
https://ncbi.nlm.nih.gov/pubmed/19299513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806941200
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