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Trolox Prevents Osteoclastogenesis by Suppressing RANKL Expression and Signaling
Excessive receptor activator of NF-κB ligand (RANKL) signaling causes enhanced osteoclast formation and bone resorption. Thus, down-regulation of RANKL expression or its downstream signals may be a therapeutic approach to the treatment of pathological bone loss. In this study, we investigated the ef...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679474/ https://ncbi.nlm.nih.gov/pubmed/19299513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806941200 |
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