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BRCA1 and RNAi factors promote small RNA- and PalB2/Rad52- mediated repair

Strong connections exist between R-loops, genome instability, and human disease(1–5). Indeed, R-loops are favoured in relevant genomic regions as regulators of certain physiological processes wherein homeostasis is typically maintained. For example, R-loop-associated transcription termination pause...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Hatchi, Elodie, Goehring, Liana, Landini, Serena, Skourti-Stathaki, Konstantina, DeConti, Derrick K., Abderazzaq, Fieda O., Banerjee, Priyankana, Demers, Timothy, Wang, Yaoyu, Quackenbush, John, Livingston, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245199/
https://ncbi.nlm.nih.gov/pubmed/33536619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-03150-2
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