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Disorder driven allosteric control of protein activity

Studies of protein allostery increasingly reveal an involvement of the back and forth order-disorder transitions in this mechanism of protein activity regulation. Here, we investigate the allosteric mechanisms mediated by structural disorder using the structure-based statistical mechanical model of...

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Pubblicato in:Curr Res Struct Biol
Autori principali: Tee, Wei-Ven, Guarnera, Enrico, Berezovsky, Igor N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244471/
https://ncbi.nlm.nih.gov/pubmed/34235479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crstbi.2020.09.001
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