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Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation

BACKGROUND: X-chromosome inactivation (XCI) is the epigenetic inactivation of one of two X chromosomes in XX eutherian mammals. The inactive X chromosome is the result of multiple silencing pathways that act in concert to deposit chromatin changes, including DNA methylation and histone modifications...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Balaton, Bradley P., Brown, Carolyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244145/
https://ncbi.nlm.nih.gov/pubmed/34187555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-021-00404-9
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